Grana Padano, one of the world’s most ancient hard cheeses, is truly beloved. It’s the most popular cheese in Italy and the most widely consumed Protected Designation of Origin (PDO) cheese in the world, with over 5 million wheels made each year with almost a quarter of Italy’s milk production. There’s good reason it’s so sought after and celebrated. The firm, crumbly wheels are luxuriously sweet, nutty, fragrant and outstanding.